W / ↑ — accelerate · run (on foot) · nose down / pitch (plane) · nose down / fly forward (chopper)
S / ↓ — brake / reverse · back up (on foot) · nose up / pitch (plane) · nose up / back off (chopper)
A / D or ← / → — steer · turn (on foot) · bank (plane) · pedal turn (chopper)
Q / E — rudder / nosewheel left · right (flying a plane) · Q draws / holsters the pistol (on foot)
F — get out of / into the vehicle · hijack any car you walk up to · ride a motorbike · fly the biplane (at Ardmore) or the chopper (Mechanics Bay heliport)
E — enter / leave a house (on foot) · ride the Sky Tower lift (at the base / on the deck)
1 / 2 / 3 — fists · knuckle dusters · baton (on foot; same key puts it away)
Mouse — look around (click the game to capture the cursor · Esc releases it)
Click / X — shoot (locks the nearest ped ahead) · swing the melee weapon · cut throttle to idle (flying)
Space — handbrake / drift (car & bike) · jump (on foot) · climb (chopper) · pull the parachute cord (mid-skydive)
Shift — sprint (on foot) · throttle up (plane) · descend (chopper)
Ctrl — crouch (on foot) · throttle down · brakes · reverse thrust (plane)
C — change camera
R — reset vehicle / bike upright · level the wings (flying)
G — raise / lower the landing gear (flying a plane) · cycle the Mirror's Edge look (otherwise)
[ / ] — previous / next radio station
\ — radio off / on
T — hold to advance time
M — toggle minimap
Tab — open / close the full map
U — pull out your phone (Uber, Tinda, Mail, Tunes, Snaps, Bank)
P — mute / unmute sound
O — mute / unmute your mic (multiplayer; the mic pill by the radar shows it)
B — flag a bad road (files a report and screenshot)